Sugar acids and derivatives
Medchemexpress LLC UDP-glucuronic acid (trisodium) | 63700-19-6 | 99.9% | 646.23 | 10 MG
UDP-glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates across biological kingdoms, including mammalian glycosaminoglycans, plant cell wall polysaccharides, and bacterial capsule glycoglycerolipids. This product is a laboratory chemical intended for research use only by qualified scientists.
- Precursor for essential glycoconjugates in various biological organisms
- Promotes migration of liver cancer cells (Huh7, SK-Hep1, SNU449) by inducing the EMT process in vitro
- Decreases E-cadherin levels and increases vimentin levels in Huh7 and SNU449 cells in vitro
- Soluble in H2O (≥ 100 mg/mL) and DMSO (20 mg/mL with warming/ultrasonic)
- Recommended storage at -20°C, sealed, away from moisture
- In solvent, recommended storage at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Tetrahydrouridine | 18771-50-1 | C9H16N2O6 | 25 MG
Tetrahydrouridine (THU) is a potent inhibitor of cytidine deaminase (CDA) that competitively blocks the enzyme's active site. It is intended for research and analytical applications, and can suppress deamination in the catabolism of cytotoxic deoxycytidine analogues.
- Potent inhibitor of cytidine deaminase (CDA)
- Competitively blocks the enzyme's active site
- Can suppress deamination in the catabolism of cytotoxic deoxycytidine analogues
- Improves Gemcitabine sensitivity in certain cell types
- Inhibits S-phase without apoptosis
- For research use only
- Analytical standard
Medchemexpress LLC Intestinal Alkaline Phosphatase Antibody (YA1559) | 100 UL
Intestinal Alkaline Phosphatase Antibody (YA1559) is a rabbit-derived, non-conjugated IgG monoclonal antibody targeting Intestinal Alkaline Phosphatase. This antibody is designed for research applications, including Western Blot (WB) and Immunohistochemistry-Paraffin (IHC-P).
- Host: Rabbit
- Clonality: Recombinant, monoclonal
- Reactivity: Human
- Isotype: IgG
- Conjugation: Non-conjugated
- Purification: Affinity chromatography
- Form: Liquid
- Storage: Stored at -20°C for 1 year, avoid repeated freeze/thaw cycles
- Application: WB (1:500-1:1000), IHC-P (1:50-1:100)
- Function: Alkaline phosphatase that can hydrolyze various phosphate compounds
- Immunogen: Synthesized peptide derived from human intestinal alkaline phosphatase
Apexbio Technology LLC Beta-Amyloid (1-11) 190436-05-6 25mg
Beta-Amyloid (1-11) (CAS 190436-05-6) is a synthetic peptide fragment derived from the N-terminus of the amyloid precursor protein comprising the amino acid sequence H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-OH This peptide represents a portion of the beta-amyloid (A ) sequence implicated in amyloidogenic pathways associated with neurodegenerative processes particularly Alzheimer s disease Beta-Amyloid (1-11) is utilized in research to investigate amyloid aggregation dynamics immunogenic epitope mapping within the A region and the biochemical properties of amyloidogenic peptides It serves as a molecular tool in studies examining the early stages of A processing clearance and interactions with cellular components
![Apexbio Technology LLC heparin cofactor II precursor fragment [Homo sapiens] 1mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000096670.png-250.jpg)
Apexbio Technology LLC heparin cofactor II precursor fragment [Homo sapiens] 1mg
Heparin cofactor II precursor fragment is a thrombin inhibitor peptide targeting human thrombin (factor IIa) It is designed to inhibit thrombin activity thereby modulating blood coagulation pathways Heparin cofactor II precursor fragment exerts its biological activity primarily through serine protease inhibition facilitated in the presence of heparin or dermatan sulfate Based on these pharmacological properties heparin cofactor II precursor fragment holds research potential in investigating thrombin inhibition mechanisms blood coagulation pathways and conditions associated with altered coagulation such as heparin cofactor II deficiency and hypercoagulability disorders
Medchemexpress LLC D-Mannoheptulose | 3615-44-9 | MFCD00006622 | 210.18 | 10 MG
D-Mannoheptulose is a 7-carbon keto sugar found in avocado. It is a specific inhibitor of D-glucose phosphorylation by hexokinase isoenzymes. This compound can block insulin release and the utilization of carbohydrates in rats. It also exhibits various functions such as antioxidant and anticancer effects, and can act as an energy source.
- Specific inhibitor of D-glucose phosphorylation by hexokinase isoenzymes
- Can block insulin release
- Can block utilization of carbohydrates in rats
- Exhibits antioxidant effects
- Shows anticancer effects
- Acts as an energy source
- Inhibits breast cancer cell line growth (MCF-7 IC50: 263.3 μg/mL)
- No significant cytotoxic effect on normal cells (HMECs IC50: 975.1 μg/mL)
Medchemexpress LLC Pentadecanoic acid-d29 | 130348-95-7 | MFCD00053332 | 271.58 | 10 MG
Pentadecanoic acid-d29 is the deuterium labeled Pentadecanoic acid. Pentadecylic acid is a saturated fatty acid with a 15-carbon backbone. It is for research use only.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
![eMolecules 3-AZABICYCLO[3.1.0]HEXANE-1-CARBONITRILE HBR | 2007919-32-4 | MFCD30471580 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183316.JPG-250.jpg)
eMolecules 3-AZABICYCLO[3.1.0]HEXANE-1-CARBONITRILE HBR | 2007919-32-4 | MFCD30471580 | 1g
AstaTech | 3-AZABICYCLO[3.1.0]HEXANE-1-CARBONITRILE HBR | 1g | 290683369 | P14880 | 95.000 | 2007919-32-4 | MFCD30471580 | 189.056 | C6H9BrN2
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Medchemexpress LLC 1-beta-D-Arabinofuranosyluracil (Standard) | 3083-77-0 | 25 MG
1-beta-D-Arabinofuranosyluracil (Standard) is an analytical standard for research and analytical applications, isolated from the Caribbean sponge *Tectitethya crypta*. This methoxyadenosine derivative exhibits diverse bioactivity, including anti-inflammatory, analgesic, and vasodilation properties. It is commonly used in qualitative, quantitative, and methodological research experiments.
- Analytical standard for research and analytical applications
- Isolated from Caribbean sponge *Tectitethya crypta*
- Exhibits anti-inflammatory, analgesic, and vasodilation properties
- Reduces proliferation of mouse lymphoma cells
- Used in HPLC, GC, and MS research experiments
- Store at 4°C, sealed, away from light and moisture
- In solvent, store at -80°C for 6 months or -20°C for 1 month (sealed, away from light and moisture)